Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep260 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Weight loss through lifestyle modification or liraglutide is associated with improvement of NAFLD severity and changes in amino acid concentrations

Khoo Joan , Koo Seok-Hwee , Ching Jianhong , Soon Gaik-Hong , Kovalik Jean-Paul

Introduction: Non-alcoholic fatty liver disease (NAFLD), defined as excess fat accumulation in the liver, is increasingly prevalent due to obesity. NAFLD may lead to steatohepatitis and eventually cirrhosis. Weight loss, either through diet and exercise or medications such as the glucagon-like peptide-1 agonist liraglutide, improves transaminitis, a marker of NAFLD severity. Visceral obesity is associated with increased plasma levels of the amino acids alanine, phenylalanine, ...